発表論文（2010年～）

 

原著論文

 

Takao, K., Akagi, Y., Tsuge, T., Harimoto, Y., Yamamoto, M., and Kodama, M. (2016). The global regulator LaeA controls biosynthesis of host-specific toxins, pathogenicity and development of Alternaria alternata pathotypes. J. Gen. Plant Pathol. 82: 121-131.

 

Takao, K., Akagi, Y., Tsuge, T., and Kodama, M. (2016). Functional characterization of putative G protein-coupled receptors in the tomato pathotype of Alternaria alternata. J. Gen. Plant Pathol. 82: 82-88.

 

Sun, Y., Feng, Z., Suzuki, A., Miyano, S., Tsuge, T., Mori, H., Suh, J.-W., Iizuka, T., Fudou, R., and Ojika, M. (2016). Biosynthesis and efficient heterologous production of haliangicin, a marine Myxobacterial polyketide antibiotic. Sci. Rep. 6: 22091.

 

Cartagena, J.A., Seki, M., Tanaka, M., Yamauchi, T., Sato, S., Hirakawa, H., and Tsuge, T. (2015). Gene expression profiles in Jatropha under drought stress and during recovery. Plant Mol. Biol. Rep. 33: 1075-1087.

 

Iida, Y., Fujiwara, K., Yoshioka, Y., and Tsuge, T. (2014). Mutation of FoVTS1, encoding a putative post-transcriptional regulator, affects asexual reproduction in the fungal plant pathogen Fusarium oxysporum. FEMS Microbiol. Lett. 351: 104-112.

 

Cartagena, J.A., and Tsuge, T. (2014). Changes in Histone H3 modifications during Jatropha curcas drought response. Philipp. Agric. Scientist 97: 53-58.

 

Takaoka, S., Kurata, M., Harimoto, Y., Hatta, R., Akimitsu, K., Yamamoto, M., and Tsuge, T. (2014). Complex regulation of secondary metabolism controlling pathogenicity in the plant pathogenic fungus Alternaria alternata. New Phytol. 202: 1297-1309.

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Tanaka, A., Cartwright, G.M., Saikia, S., Kayano, Y., Takemoto, D., Kato, M., Tsuge, T., and Scott, B. (2013). ProA, a transcriptional regulator of fungal fruiting body development, regulates leaf hyphal network development in the Epichloë festucae-Lolium perenne symbiosis. Mol. Microbiol. 90: 551-568.

 

Kheder, A.A., Akagi, Y., Akamatsu, H., Yanaga, K., Maekawa, N., Otani, H., Tsuge, T., and Kodama, M. (2012). Functional analysis of the melanin biosynthesis genes ALM1 and BRM2-1 in the tomato pathotype of Alternaria alternata. J. Gen. Plant Pathol. 78: 30-38.

 

Kheder, A.A., Akagi, Y., Tsuge, T., and Kodama, M. (2012). Functional analysis of the ceramide synthase gene ALT7, a homolog of the disease resistance gene Asc1, in the plant pathogen Alternaria alternata. J. Plant Pathol. Microbiol. S2: 001.

 

Imazaki, A., Tanaka, A., Harimoto, Y., Yamamoto, M., Akimitsu, K., Park, P., and Tsuge, T. (2010). Contribution of peroxisomes to secondary metabolism and pathogenicity in the fungal plant pathogen Alternaria alternata. Eukaryot. Cell 9: 682-694.

 

Miyamoto, Y., Masunaka, A., Tsuge, T., Yamamoto, M., Ohtani, K., Fukumoto, T., Gomi, K., Peever, T. L., Tada, Y., Ichimura, K., and Akimitsu, K. (2010). ACTTS3 encoding a polyketide synthase is essential for the biosynthesis of ACT-toxin and pathogenicity in the tangerine pathotype of Alternaria alternata. Mol. Plant-Microbe Interact. 23: 406-414.

 

Ajiro, N., Miyamoto, Y., Masunaka, A., Tsuge, T., Yamamoto, M., Ohtani, K., Fukumoto, T., Gomi, K., Peever, T. L., Izumi, Y., Tada, Y., and K. Akimitsu (2010). Role of the host-selective ACT-toxin synthesis gene ACTTS2 encoding an enoyl-reductase in pathogenicity of the tangerine pathotype of Alternaria alternata. Phytopathology 100: 120-126.

 

著書・総説

 

柘植尚志 (2016). 宿主特異的毒素研究. 植物感染生理談話会論文集（第51号）感染生理談話会の50年～古きを温ねて、新しきを知る～(中屋敷均ら編), 日本植物病理学会, 東京, pp. 57-69.

 

柿嶌眞，景山幸次，埋橋志穂美，百町満朗，有江力，土佐幸雄，柘植尚志 (2015). 第２編 第１章 ３植物菌類学. 日本植物病理学会100年史, 日本植物病理学会, 東京, pp. 50-67.

 

Akimitsu, K., Ohtani, K., Shimagami, T., Katsumoto, M., Igarashi, C., Tanaka, S., Matsuoka, S., Mochizuki, S., Tsuge, T., Yamamoto, M., Kodama, M., Ichimura, K., and Gomi, K. (2016). Citrus as a molecular contact point for co-evolution of Alternaria pathogens. Physiol. Mol. Plant Pathol. 95: 93-96.

 

Tsuge, T., Harimoto, Y., Akagi, Y., Hanada, K., Kodama, M., Akimitsu, K., and Yamamoto, M. (2016). Evolution of pathogenicity controlled by small dispensable chromosomes in Alternaria alternata pathogens. Physiol. Mol. Plant Pathol. 95: 27-31.

 

児玉基一朗, 赤木靖典, 髙尾和実, 柘植尚志 (2015). マイコトキシンとファイトトキシン－似て非なるもの，あるいは全く同じもの－. JSM Mycotoxins 65:57-62.

 

Akimitsu, K., Tsuge, T., Kodama, M., Yamamoto, M. and Otani, H. (2014). Alternaria host-selective toxins: determinant factors of plant disease. J. Gen. Plant Pathol. 80: 109-122.

 

児玉基一朗, 赤木靖典, 高尾和実, 難波栄二, 山本幹博, 秋光和也, 柘植尚志 (2014). ゲノム解析からみた植物病原糸状菌の二次代謝産物生合成系と病原性の進化・多様性. 日本植物病理学会報 80: 207-216.

 

Li, Y., Aldwinckle, H.S., Sutton, T., Tsuge, T., Kang, G., Pei-Hua Cong, P-H., and Cheng, Z.-M. (2013). Interactions of apple and Alternaria alternata apple pathotype. Crit. Rev. Plant Sci. 32: 141-150.

 

秋光和也, 柘植尚志, 児玉基一朗, 山本幹博, 尾谷　浩 (2014). Alternaria属菌の宿主特異的毒素：植物病害の決定因子. 日本植物病理学会報 80 (特集号): 49-55.

 

Tsuge, T., Harimoto, Y., Akimitsu, K., Ohtani, K., Kodama, M., Akagi, Y., Egusa, M., Yamamoto, M. and Otani, H. (2013). Host-selective toxins produced by the plant pathogenic fungus Alternaria alternata. FEMS Microbiol. Rev. 37: 44-66.

 

赤木靖典, 柘植尚志, 児玉基一朗 (2013). Alternaria属菌の病原性進化. 植物防疫 76: 147-151.

 

児玉基一朗, 赤木靖典, 高尾和実, 柘植尚志 (2012). 植物病原糸状菌における二次代謝産物生合成と病原性－ゲノム解析からみた進化・多様性－. 植物感染生理談話会論文集（第47号）植物―病原微生物の相互作用研究の新展開 (鈴木一美, 泉津弘佑編), 日本植物病理学会, 東京, pp. 111-123.

 

 

発表論文（2000年～2009年）

 

原著論文

 

Egusa, M., Akamatsu, H., Tsuge, T., Otani, H., and Kodama, M. (2009). Induced resistance in tomato plants to the toxin-dependent necrotrophic pathogen Alternaria alternata. Physiol. Mol. Plant Pathol. 73: 67-77.

 

Egusa, M., Ochi, H., Tsuge, T., Otani, H., and Kodama, M. (2009). Identification of putative defense-related genes in Japanese pear against Alternaria alternata infection using suppression subtractive hybridization and expression analysis. J. Gen. Plant Pathol. 75: 119-124.

 

Akagi, Y., Taga, M., Yamamoto, M., Tsuge, T., Fukumasa-Nakai, Y., Otani, H., and Kodama, M. (2009). Chromosome constitution of hybrid strains constructed by protoplast fusion between the tomato and strawberry pathotype of Alternaria alternata. J. Gen. Plant Pathol. 75: 101-109.

 

Miyamoto, Y., Isshiki, Y., Honda, A., Masunaka, A., Tsuge, T., Yamamoto, M., Ohtani, K., Fukumoto, T., Gomi, K., Peever, T. L., and Akimitsu, K. (2009). Function of genes encoding acyl-CoA synthetase and enoyl-CoA hydratase for host-selective ACT-toxin biosynthesis in the tangerine pathotype of Alternaria alternata. Phytopathology 99: 369-377.

 

Nakayama, N., Tsuge, T., Asakawa, S., and Kimura, M. (2009). Morphology, host range and phylogenetic diversity of Sphingomonas phages in the floodwater of Japanese paddy field. Soil Sci. Plant Nutri. 55: 53-64.

 

Miyamoto, Y., Masunaka, A., Tsuge, T., Yamamoto, M., Ohtani, K., Fukumoto, T., Gomi, K., Peever, T. L., and Akimitsu, K. (2008). Functional analysis of a multi-copy host-selective ACT-toxin biosynthesis gene in the tangerine pathotype of Alternaria alternata using RNA silencing. Mol. Plant-Microbe Interact. 21: 1591-1599.

 

Iida, Y., Kurata, T., Harimoto, Y., and Tsuge, T. (2008). Nitrite reductase gene upregulated during conidiation is involved in macroconidium formation in Fusarium oxysporum. Phytopathology 98: 1099-1106.

 

Harimoto, Y., Tanaka, T., Kodama, M., Yamamoto, M., Otani, H., and Tsuge, T. (2008). Multiple copies of AMT2 are prerequisite for the apple pathotype of Alternaria alternata to produce enough AM-toxin for expressing pathogenicity. J. Gen. Plant Pathol. 74: 222-229.

 

Harimoto, Y., Hatta, R., Kodama, M., Yamamoto, M., Otani, H., and Tsuge, T. (2007). Expression profiles of genes encoded by the supernumerary chromosome controlling AM-toxin biosynthesis and pathogenicity in the apple pathotype of Alternaria alternata. Mol. Plant-Microbe Interact. 20: 1463-1476.

 

Iida, Y., Ohara, T., and Tsuge, T. (2007). Identification of genes with changes in transcription levels caused by mutations in conidiation regulator genes REN1 and FoSTUA in Fusarium oxysporum. J. Gen. Plant Pathol. 73: 158-167.

 

Imazaki, I., Kurahashi, M., Iida, Y., and Tsuge, T. (2007). Fow2, a Zn(II)2Cys6-type transcription regulator, controls plant infection of the vascular wilt fungus Fusarium oxysporum. Mol. Microbiol. 63: 737-753.

 

Hatta, R., Shinjo, A., Ruswandi, S. R., Kitani, K., Yamamoto, M., Akimitsu, K., and Tsuge, T. (2006). DNA transposon fossils present on the conditionally dispensable chromosome controlling AF-toxin biosynthesis and pathogenicity of Alternaria alternata. J. Gen. Plant Pathol. 72: 210-219.

 

Feng, Z., Qi, J., Tsuge, T., Oba, Y., Sakagami, Y., and Ojika, M. (2006). Biosynthesis of 2’-O-methylmyxalamide D in the myxobacterium Cystobacter fuscus: a polyketide synthase-nonribosomal peptide synthetase system for the myxalamide D skelton and a methyltransferase for the final O-methylation. Biosci. Biotechnol. Biochem. 70: 699-705.

 

Iida, Y., Ohara, T., and Tsuge, T. (2006). Identification of genes up-regulated during conidiation of Fusarium oxysporum through expressed sequence tag analysis. Fungal Genet. Biol. 43: 179-189.

 

Feng, Z., Qi, J., Tsuge, T., Oba, Y., Kobayashi, T., Suzuki, Y., Sakagami, Y., and Ojika, M. (2005). Construction of a bacterial artificial chromosome library for a myxobacterium of the genus Cystobacter and characterization of the biosynthetic gene cluster. Biosci. Biotechnol. Biochem. 69: 1372-1380.

 

Masunaka, A., Ohtani, K., Peever, T. L., Timmer, L. W., Tsuge, T., Yamamoto, M., Yamamoto, H., and Akimitsu, K. (2005). An isolate of Alternaria alternata that is pathogenic to both tangerines and rough lemon and produces two host-selective toxins, ACT- and ACR-toxins. Phytopathology 95: 241-247.

 

Ruswandi, S. R., Kitani, K., Akimitsu, K., Tsuge, T., Shiraishi, T., and Yamamoto, M. (2005). Structural analysis of cosmid clone pcAFT-2 carrying AFT10-1 encoding an acyl-CoA dehydrogenase involved in AF-toxin production in the strawberry pathotype of Alternaria alternata. J. Gen. Plant Pathol. 71: 107-116.

 

Ito, K., Tanaka, T., Hatta, R., Yamamoto, M., Akimitsu, K., and Tsuge, T. (2004). Dissection of the host range of the fungal plant pathogen Alternaria alternata by modification of secondary metabolism. Mol. Microbiol. 52: 399-411.

 

Kusumoto, S., Aeny, T. N., Mujimu, S., Ginting, C., Tsuge, T., Tsuyumu, S., and Takikawa, Y. (2004). Occurrence of blood disease of banana in south Sumatra, Indonesia. J. Gen. Plant Pathol. 70: 45-49.

 

Ohara, T., and Tsuge, T. (2004). FoSTUA, encoding a basic helix-loop-helix protein, differentially regulates development of three kinds of asexual spores, macroconidia, microconidia, and chlamydospores, in the fungal plant pathogen Fusarium oxysporum. Eukaryot. Cell 3: 1412-1422.

 

Ohara, T., Inoue, I., Namiki, F., Kunoh, H., and Tsuge, T. (2004). REN1 is required for development of microconidia and macroconidia, but not of chlamydospores, in the plant pathogenic fungus Fusarium oxysporum. Genetics 166: 113-124.

 

Hatta, R., Ito, K., Hosaki, Y., Tanaka, T., Tanaka, A., Yamamoto, M., Akimitsu, K., and Tsuge, T. (2002). A conditionally dispensable chromosome controls host-specific pathogenicity in the fungal plant pathogen Alternaria alternata. Genetics 161: 59-70.

 

Inoue, I., Namiki, F., and Tsuge, T. (2002). Plant colonization by the vascular wilt fungus Fusarium oxysporum requires FOW1, a gene encoding a mitochondrial protein. Plant Cell 14: 1869-1883.

 

Inoue, I., Ohara, T., Namiki, F., and Tsuge, T. (2001). Isolation of pathogenicity mutants of Fusarium oxysporum f. sp. melonis by insertional mutagenesis. J. Gen. Plant Pathol. 67: 191-199.

 

Namiki, F., Matsunaga, M., Okuda, M., Inoue, I., Nishi, K., Fujita, Y., and Tsuge, T. (2001). Mutation of an arginine biosynthesis gene causes reduced pathogenicity in Fusarium oxysporum f. sp. melonis. Mol. Plant-Microbe Interact. 14: 580-584.

 

Tanaka, A., and Tsuge, T. (2001). Reporter gene analysis of AKT3-1 and AKT3-2 expression during conidial germination of the Japanese pear pathotype of Alternaria alternata. J. Gen. Plant Pathol. 67: 15-22.

 

Kaneko, I., Tanaka, A., and Tsuge, T. (2000). REAL: an LTR retrotransposon of the plant pathogenic fungus Alternaria alternata. Mol. Gen. Genet. 263: 625-634.

 

Masunaka, A., Tanaka, A., Tsuge, T., Peever, T., Timmer, L.W., Yamamoto, M., Yamamoto, H., and Akimitsu, K. (2000). Distribution and characterization of AKT homologs in the tangerine pathotype of Alternaria alternata. Phytopathology 90: 762-768.

 

Namiki, F., Shimizu, K., Satou, K., Hirabayashi, T., Nishi, K., Kayamura, T., and Tsuge, T. (2000). Occurrence of Fusarium oxysporum f. sp. melonis race 1 in Japan. J. Gen. Plant Pathol. 66: 12-17.

 

Tanaka, A., and Tsuge, T. (2000). Structural and functional complexity of the genomic region controlling AK-toxin biosynthesis and pathogenicity in the Japanese pear pathotype of Alternaria alternata. Mol. Plant-Microbe Interact. 13: 975-986.

 

著書・総説

 

柘植尚志 (2009). 第6章病原体の病原性発現機構　3. 糸状菌の病原性遺伝子の発現機構. 植物病理学(眞山慈志, 難波成任編), 文永堂出版, 東京, pp. 183-186.

 

Kodama, M., Akagi, Y., Akamatsu, H., Otani, H., Yamamoto, M. and Tsuge, T. (2008). A gene cluster on a conditionally dispensable chromosome controlling AAL-toxin biosynthesis and pathogenicity in the tomato pathotype of Alternaria alternata. In: Biology of Plant-Microbe Interactions Vol. 6 (Lorito, M., Woo, A.L., Scale, F. eds.), International Society of Molecular Plant-Microbe Interactions, St. Paul, MN, USA, Paper No. 18 (CD-Rom).

 

柘植尚志, 今崎伊織, 神田裕之, 倉橋　真, 北山　唯, 倉田智彬, 近田佳奈, 飯田祐一郎, 小原敏明, 播本佳明 (2008). Fusarium oxysporumの病原性. 土壌伝染病談話会レポート 24: 33-43.

 

柘植尚志 (2008). III. 農業と微生物2.5植物と病原微生物の相互作用 (2)病原性発現機構. 微生物の事典(渡辺　信ら編), 朝倉書店, 東京, pp. 201-202.

 

Arora, D., Berka, R., Kempken, F., Khachatourians, G. G., Loftus, B., Lang, B. F., Lee, Y.-H., Macino, G., May, G. S., Nelson, M. A., Nevalainen, H., Payne, G. A., Prade, R., Rosa, A. L., Tsuge, T., Wostemeyer, J., Yarden, O., and Yaver, D. S. Eds. (2006). Applied Mycology and Biotechnology Vol. 6 Bioinformatics. Elsevier Science, Amsterdam, The Netherlands.

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柘植尚志, 塩谷　浩, 田中愛子, 八田理恵子, 伊藤　芳, 西川理英子, 今崎亜依, 播本佳明, 高岡信也, 新城明久, 加藤真理子 (2005). Alternaria alternata病原菌の宿主特異的毒素生合成 −デカトリエン酸エステル毒素を生産する病原菌について. 植物感染生理談話会論文集（第41号）植物・病原体相互反応における特異性決定機構（山本弘幸, 秋光和也編）, 日本植物病理学会, 東京, pp. 85-94.

 

Tsuge, T., Hatta, R., Ito, K., Tanaka, T., Ruswandi, S., Kitani, K., Harimoto, Y., Takaoka, S., Masunaka, A., Akamatsu, H., Akimitsu, K., Kodama, M., Yamamoto, M., and Otani, H. (2005). Conditionally dispensable chromosomes controlling pathogenicity of Alternaria alternata. In: Genomic and Genetic Analysis of Plant Parasitism and Defence (S. Tsuyumu et al., eds.), The American Phytopathological Society Press, St. Paul, MN, USA, pp. 50-60.

 

山本幹博, 柘植尚志 (2004). AF毒素とイチゴ黒斑病菌の病原性. 植物病の探究(高松　進ら編), 久能均先生退官記念出版会, 津, pp. 75-81.

 

奥田誠一, 高浪洋一, 難波成任, 陶山一雄, 羽柴輝良, 百町満朗, 柘植尚志, 内藤繁男 共著 (2004). 最新植物病理学. 朝倉書店, 東京.

 

島本　功, 渡辺雄一郎, 柘植尚志 監修 (2004). 植物細胞工学シリーズ19 新版分子レベルから見た植物の耐病性, 秀潤社, 東京.

 

柘植尚志, 露無慎二 (2004). 糸状菌と細菌の病原性. 植物感染生理談話会論文集（第40号）自他識別と応答のバイオフロンティア（羽柴輝良, 高橋英樹編）, 日本植物病理学会, 東京, pp. 111-125.

 

柘植尚志 (2003). Alternaria alternataの病原性遺伝子に関する研究. 日植病報 69: 172-174.

 

Tsuge, T. (2003). Studies on pathogenicity genes of Alternaria alternata pathogens. J. Gen. Plant Pathol. 69: 418-420.

 

柘植尚志, 児玉基一朗, 秋光和也, 山本幹博 (2002). 植物病原菌の宿主特異的毒素生合成の分子機構—毒素生合成遺伝子群をコードするCD染色体. 化学と生物 40: 654-659.

 

柘植尚志, 井上伊織, 小原敏明, 神田裕之, 並木史郎 (2002). 土壌病原菌の遺伝子解析 —病原性関連遺伝子. 土壌伝染病談話会レポート 21: 91-105.

 

Tanaka, A., Nishikawa, R. and Tsuge, T. (2001). Identification of AKT3-2 and AKTR-2 genes required for AK-toxin biosynthesis in the Japanese pear pathotype of Alternaria alternata. In: Plant Diseases and Their Control (S. Zeng et al., eds.), China Agricultural Scientech Press, Beijing, China, pp. 154-158.

 

Tsuge, T., Tanaka, A., Nishikawa, R., Hatta, R., Ito, K., Masunaka, A., Hosaki, Y., Akimitsu, K. and Yamamoto, M. (2001). Molecular genetics of host-specific toxin biosynthesis in Alternaria alternata. In: Delivery and Perception of Pathogen Signals in Plants (N. Keen et al., eds.), The American Phytopathological Society Press, St. Paul, MN, pp. 87-96.

 

柘植尚志, 田中愛子, 八田理恵子, 伊藤　芳, 西川理英子, 今崎亜依, 保崎佳嗣, 山本幹博, 増中　章, 秋光和也 (2000). Alternaria alternata病原菌群の宿主特異的毒素生合成の分子機構. 植物感染生理談話会論文集（第36号）植物と微生物相互作用の夜明け (奥野哲郎, 曳地康史編), 日本植物病理学会, 東京, pp. 16-25.

 

Tsuge, T., Hatta, R., Ito, K., Hosaki, Y., Tanaka, A., Nishikawa, R., Imazaki, A., Masunaka, A., Akimitsu, K. and Yamamoto, M. (2000). The gene clusters required for host-specific toxin biosynthesis and pathogenicity in Alternaria alternata. Proceedings of the 7th International Symposium of Mycological Society of Japan “Fungus-Plant Interactions: From Parasitism to Symbiosis“, Tsukuba, pp. 15-18.

 

 

発表論文（～1999年）

 

原著論文

 

Kaneko, I., Owaki, M., and Tsuge, T. (1999). Intracellular localization and expression of the plasmid pAAT56 in the Japanese pear pathotype of Alternaria alternata. Ann. Phytopathol. Soc. Jpn. 65: 25-31.

 

Kawamura, C., Tsujimoto, T., and Tsuge, T. (1999). Targeted disruption of a melanin biosynthesis gene affects conidial development and UV tolerance in the Japanese pear pathotype of Alternaria alternata. Mol. Plant-Microbe Interact. 12: 59-63.

 

Tanaka, A., Shiotani, H. Yamamoto, M., and Tsuge, T. (1999). Insertional mutagenesis and cloning of the genes required for biosynthesis of the host-specific AK-toxin in the Japanese pear pathotype of Alternaria alternata. Mol. Plant-Microbe Interact. 12: 691-702.

 

Hyakumachi, M., Mushika, T., Ogiso, Y., Toda, T., Kageyama, K., and Tsuge, T. (1998). Characterization of a new cultural type (LP) of Rhizoctonia solani AG2-2 isolated from warm-season turfgrasses, and its genetic differentiation from other cultural types. Plant Pathol. 47: 1-9.

 

Namiki, F., Shiomi, T., Nishi, K., Kayamura, T. and Tsuge, T. (1998). Pathogenic and genetic variation in the Japanese strains of Fusarium oxysporum f. sp. melonis. Phytopathology 88: 804-810.

 

Okuda, M., Ikeda, K., Namiki, F., Nishi, K., and Tsuge, T. (1998). Tfo1: an Ac-like transposon of the plant pathogenic fungus Fusarium oxysporum. Mol. Gen. Genet. 258: 599-607.

 

Kaneko, I., Katsuya, S., and Tsuge, T. (1997). Structural analysis of the plasmid pAAT56 of the filamentous fungus Alternaria alternata. Gene 203: 51-57.

 

Katsuya, S., Kaneko, I., Owaki, M., Ishikawa, K., Tsujimoto, T., and Tsuge, T. (1997). Circular DNA plasmid in the phytopathogenic fungus Alternaria alternata: its temperature-dependent curing and association with pathogenicity. Genetics 146: 111-120.

 

Kawamura, C., Moriwaki, J., Kimura, N., Fujita, Y., Fuji, S., Hirano, K., Koizumi, S., and Tsuge, T. (1997). The melanin biosynthesis genes of Alternaria alternata can restore pathogenicity of the melanin-deficient mutants of Magnaporthe grisea. Mol. Plant-Microbe Interact. 10: 446-453.

 

Kusaba, M., and Tsuge, T. (1997). Mitochondrial DNA variation in host-specific toxin-producing pathogens in the genus Alternaria. Ann. Phytopathol. Soc. Jpn. 63: 463-469.

 

Takano, Y., Kubo, Y., Kawamura, C., Tsuge, T., and Furusawa, I. (1997). The Alternaria alternata melanin biosynthesis gene restores appressorial melanization and penetration of cellulose membranes in the melanin-deficient albino mutant of Colletotrichum lagenarium. Fungal Genet. Biol. 21: 131-140.

 

Adachi, Y., Watanabe, H., and Tsuge, T. (1996). Relationships between genetic polymorphisms and fungicide resistance within Alternaria alternata. Phytopathology 86: 1248-1254.

 

Namiki, F., Nishi, K., and Tsuge, T. (1996). Genetic relatedness among the phytopathogenic variants in Fusarium oxysporum causing wilts of the cucurbits. JARQ 30: 159-165.

 

Kusaba, M., and Tsuge, T. (1995). Phylogeny of Alternaria fungi known to produce host-specific toxins on the basis of variation in internal transcribed spacers of ribosomal DNA. Curr. Genet. 28: 491-498.

 

Lee, S-S., and Tsuge, T. (1995). Effect of host-specific AF-toxin I produced by the strawberry pathotype of Alternaria alternata on protein synthesis and extracellular polysaccharide accumulation in strawberry protoplasts. Korean J. Plant Pathol. 11: 318-323.

 

Shiotani, H., and Tsuge, T. (1995). Efficient gene targeting in the filamentous fungus Alternaria alternata. Mol. Gen. Genet. 248: 142-150.

 

Tanabe, K., Park, P., Tsuge, T., Kohmoto, K., and Nishimura, S. (1995). Characterization of melanin-deficient mutants of Alternaria alternata Japanese pear pathotype and their pathogenicity. Ann. Phytopathol. Soc. Jpn. 61: 27-33.

 

Adachi, Y., and Tsuge, T. (1994). Coinfection by different isolates of Alternaria alternata in single black spot lesions of Japanese pear leaves. Phytopathology 84: 447-451.

 

Kusaba, M., and Tsuge, T. (1994). Nuclear ribosomal DNA variation and pathogenic specialization in Alternaria fungi known to produce host-specific toxins. Appl. Environ. Microbiol. 60: 3055-3062.

 

Namiki, F., Shiomi, T., Kayamura, T., and Tsuge, T. (1994). Characterization of the formae speciales of Fusarium oxysporum causing wilts of cucurbits by DNA fingerprinting with nuclear repetitive DNA sequences. Appl. Environ. Microbiol. 60: 2684-2691.

 

Adachi, Y., Watanabe, H., Tanabe, K., Doke, N., Nishimura, S., and Tsuge, T. (1993). Nuclear ribosomal DNA as a probe for genetic variability in the Japanese pear pathotype of Alternaria alternata. Appl. Environ. Microbiol. 59: 3197-3205.

 

Kimura, N., and Tsuge, T. (1993). Gene cluster involved in melanin biosynthesis of the filamentous fungus Alternaria alternata. J. Bacteriol. 175: 4427-4435.

 

Hayashi, N., Yamamoto, M., Tsuge, T., and Nishimura, S. (1992). Comparison of parasitic fitness between two pathotypes of Alternaria alternata to Japanese pear. Ann. Phytopathol. Soc. Jpn. 58: 734-740.

 

Lee, S-S., Kawakita, K., Tsuge, T. and Doke, N. (1992). Stimulation of phospholipase A2 activity in strawberry cells treated with AF-toxin I produced by Alternaria alternata strawberry pathotype. Physiol. Mol. Plant Pathol. 41: 283-294.

 

Lee, S-S., Tsuge, T., Doke, N., Nakatsuka, S., and Nishimura, S. (1992). Protective effect of homologues of host-specific AF-toxin I produced by Alternaria alternata strawberry pathotype on strawberry cells. J. Phytopathol. 135: 177-186.

 

Orolaza, N.P., Kawaguchi, I., Tsuge, T., and Doke, N. (1992). Effect of AL-toxin produced by Alternaria alternata tomato pathotype on cultured roots of tomato. Ann. Phytopathol. Soc. Jpn. 58: 411-415.

 

Park, P., Lee, S-S., Ohno, T., Tsuge, T., and Nishimura, S. (1992). Slightly damaged type of plasma membrane modification in strawberry leaves treated with AF-toxin I produced by Alternaria alternata strawberry pathotype. Ann. Phytopathol. Soc. Jpn. 58: 431-445.

 

Toyota, K., Tsuge, T., and Kimura, M. (1992). Potential application of genetic transformants of Fusarium oxysporum f. sp. raphani for assessing the fungal autecology. Soil Biol. Biochem. 24: 489-494.

 

Xiao, J-Z., Tsuge, T., and Doke, N. (1992). Further evaluation of the significance of BZR-toxin produced by Bipolaris zeicola race 3 in the pathogenesis on rice and maize plants. Physiol. Mol. Plant Pathol. 40: 359-370.

 

Kawaguchi, I., Orolaza, N.P., Tsuge, T., Nishimura, S., and Doke, N. (1991). Changes in amino acid and amine contents of susceptible tomato infected with Alternaria alternata tomato pathotype and treated with AL-toxin. Ann. Phytopathol. Soc. Jpn. 57: 526-533.

 

Lee, S-S., Tsuge, T., Doke, N., and Nishimura, S. (1991). Effect of host-specific AF-toxins from Alternaria alternata strawberry pathotype on viability of strawberry cultured cells. Ann. Phytopathol. Soc. Jpn. 57: 671-679.

 

Xiao, J-Z., Tsuge, T., Doke, N., Nakatsuka, S., Tsuda, M., and Nishimura, S. (1991). Rice-specific toxins produced by Bipolaris zeicola, race 3; evidence for role as pathogenicity factors for rice and maize plants. Physiol. Mol. Plant Pathol. 38: 67-82.

 

Feng, B-N., Nakatsuka, S., Goto, T., Tsuge, T., and Nishimura, S. (1990). Biosynthesis of host-selective toxins produced by Alternaria alternata pathogens. I. (8R,9S)-9,10-epoxy-8-hydroxy-9-methyl-(2E,4Z,6E)-trienoic acid as a biological precursor of AK-toxins. Agric. Biol. Chem. 54: 845-848.

 

Hayashi, N., Tanabe, K., Tsuge, T., Nishimura, S., Kohmoto, K., and Otani, H. (1990). Determination of host-selective toxin production during spore germination of Alternaria alternata by high performance liquid chromatography. Phytopathology 80: 1088-1091.

 

Nakatsuka, S., Feng, B-N., Goto, T., Tsuge, T., and Nishimura, S. (1990). Biosynthetic origin of (8R,9S)-9,10-epoxy-8-hydroxy-9-methyl-(2E,4Z,6E)-trienoic acid, a precursor of AK-toxins produced by Alternaria alternata Japanese pear pathotype. Phytochemistry 29: 1529-1531.

 

Tsuge, T., Nishimura, S., and Kobayashi, H. (1990). Efficient integrative transformation of the phytopathogenic fungus Alternaria alternata mediated by the repetitive rDNA sequences. Gene 90: 207-214.

 

Tanabe, K., Tsuge, T., and Nishimura, S. (1989). Potential application of DNA restriction fragment length polymorphisms in the ecological studies of Alternaria alternata Japanese pear pathotype. Ann. Phytopathol. Soc. Jpn. 55: 361-365.

 

Tsuge, T., Kobayashi, H., and Nishimura, S. (1989). Organization of ribosomal RNA genes in Alternaria alternata Japanese pear pathotype, a host-selective AK-toxin-producing fungus. Curr. Genet. 16: 267-272.

 

Hayashi, N., Tsuge, T., Kobayashi, H., and Nishimura, S. (1988). The presence of double-stranded RNAs in Alternaria alternata Japanese pear pathotype and their participation in AK-toxin productivity. Ann. Phytopathol. Soc. Jpn. 54: 250-252.

 

Tsuge, T., Hayashi, N., and Nishimura, S. (1987). Selection of auxotrophic mutants and heterokaryosis in Alternaria alternata. Ann. Phytopathol. Soc. Jpn. 53: 182-190.

 

Tsuge, T., Hayashi, N., and Nishimura S. (1986). Metabolic regulation of host-specific toxin production in Alternaria alternata pathogens (3). Instability of pathogenicity in field isolates of A. alternata Japanese pear pathotype. Ann. Phytopathol. Soc. Jpn. 52: 488-491.

 

Tsuge, T., Kobayashi, H., and Nishimura S. (1986). Metabolic regulation of host-specific toxin production in Alternaria alternata pathogens (4). Molecular cloning of mRNA in AK-toxin producing isolate. Ann. Phytopathol. Soc. Jpn. 52: 690-699.

 

Tsuge, T., Nishimura S., Omura, S., Kohmoto, K., and Otani, H. (1985). Metabolic regulation of host-specific toxin production in Alternaria alternata pathogens (2). Suppression of toxin production from germinating spores by chemical treatment. Ann. Phytopathol. Soc. Jpn. 51: 277-284.

 

Tsuge, T., and Nishimura S. (1984). Metabolic regulation of host-specific toxin production in Alternaria alternata pathogens (1). Suppression of toxin production from germinating spores under high temperature stress. Ann. Phytopathol. Soc. Jpn. 50: 189-196.

 

著書・総説

 

Tsuge, T., Tanaka, A., Hatta, R., Shiotani, H., Kusaba, M., Akimitsu, K. and Yamamoto, M. (1999). Molecular basis of pathogenic variation in the filamentous fungus Alternaria alternata. In: Diversity and Use of Agricultural Microorganisms (K. Kato et al., eds.), Research Council Secretariat of MAFF and National Institute of Agrobiological Resources, Tsukuba, pp. 223-235.

 

Tsuge, T., Tanaka, A., Hatta, R. and Shiotani, H. (1998). Molecular analysis of AK-toxin biosynthesis in the Japanese pear pathotype of Alternaria alternata. In: Molecular Genetics of Host-Specific Toxins in Plant Disease (K. Kohmoto and O.C. Yoder, eds.), Kluwer Academic Publishers, Dordrecht, The Netherlands, pp. 43-52.

 

柘植尚志 (1997). 植物病原体の遺伝子解析 他４項目. 植物保護の事典（岡崎正規ら編）, 朝倉書店, 東京, pp. 452-457, 459-460.

 

Tsuge, T., Kusaba, M., Shiotani, H., Tanaka, A., Katsuya, S., Owaki, M., and Kaneko, I. (1996). Molecular aspects of pathogenic specialization in Alternaria alternata pathogens. In: Molecular Aspects of Pathogenicity and Host Resistance: Requirements for Signal Transduction (D. Mills et al., eds.), The American Phytopathological Society Press, St. Paul, MN, USA, pp. 129-138. 

 

Kohmoto, K., Otani, H., and Tsuge, T. (1995). Alternaria alternata pathogens. In: Pathogenesis and Host Specificity in Plant Diseases: Histopathological, Biochemical, Genetic and Molecular Bases, Vol. II Eukaryotes (K. Kohmoto, U. S. Singh and R. P. Singh, eds.), Pergamon, Oxford, UK, pp. 51-63.

 

柘植尚志 (1995). 植物病原糸状菌の宿主特異的毒素. バイオサイエンスとインダストリー 53: 397-401.

 

Tsuge, T., and Kusaba, M. (1995). Pathogenic specialization in the phytopathogenic fungus, Alternaria alternata. Proceedings of the '95 Japan-Korea Joint Seminar for Collaborative Researches on Biological Sciences “Biological Response to Environment”. pp. 34-38.

 

 

Tsuge, T., Kusaba, M., Katsuya, S., Shiotani, H., Kimura, N., and Adachi, Y. (1994). Molecular Biology of AK-toxin production by the Japanese pear pathotype of Alternaria alternata. In: Host-Specific Toxin: Biosynthesis, Receptor and Molecular Biology (K. Kohmoto and O. C. Yoder, eds.), Tottori University Press, Tottori, Japan, pp. 239-250.

 

並木史郎, 西　和文, 柘植尚志 (1994). DNAからみたFusarium oxysporumの病原性分化. 日本植物病理学会九州部会シンポジウム論文集, 日本植物病理学会, 東京, pp.45-66.

 

柘植尚志, 草場基章, 勝屋　聡, 塩谷　浩, 木村教男 (1994). Alternaria alternata病原菌の病原性の分子解析. 植物感染生理談話会論文集（第30号）植物疾病におけるGene-for-Gene説の分子的基盤（木村郁夫編）, 日本植物病理学会, 東京, pp. 21-30.

 

柘植尚志, 草場基章, 足立嘉彦 (1993). Alternaria属菌のRFLP解析. 植物感染生理談話会論文集（第29号）分子植物病理学の最近の進歩(八重樫博志編), 日本植物病理学会, 東京, pp. 123-132.

 

柘植尚志, 草場基章, 足立嘉彦 (1992). 植物病原糸状菌のRFLP. 植物防疫 46: 315-319.

 

柘植尚志 (1991) 宿主特異的毒素と病原性. 植物感染生理学最近の進歩(奥　八郎ら編), 植物感染生理学最近の進歩刊行会, 名古屋, pp. 23-32.

 

Tsuge, T., and Kobayashi, H. (1991). Molecular analysis of genes for pathogenicity of Alternaria alternata Japanese pear pathotype, a host-specific toxin producer. In: Molecular Strategies of Pathogens and Host Plants (S. S. Patil, et al., eds.), Springer-Verlag, New York, NY, USA, pp. 119-129.

柘植尚志 (1991). 植物病原糸状菌Alternaria alternataの宿主特異的毒素. 土と微生物 37: 15-25.

 

柘植尚志, 足立嘉彦 (1991). DNAからみたAlternariaの生態. IGEシリーズ12 植物病原体の分子生態(菊本敏雄編), 東北大学遺伝生態研究センター, 仙台, pp. 47-58.

 

柘植尚志, 塩谷　浩, 木村教男 (1991). Alternaria alternataの宿主特異的毒素生産遺伝子の単離に向けて. 植物感染生理談話会論文集（第27号）生物相互間の認識機構(久能　均編), 日本植物病理学会, 東京, pp. 66-75.

 

Tsuge, T., Kobayashi, H., and Nishimura, S. (1989). Specific gene expression in the host-selective toxin producer, Alternaria alternata, and its genetic transformation with high efficiency. In: Host-Specific Toxin: Recognition and Specificity Factors in Plant Diseases (K. Kohmoto and R. D. Durbin, eds.), Tottori University Press, Tottori, Japan, pp. 124-134.

 

柘植尚志, 小林裕和, 西村正暘 (1989). 植物病原糸状菌の病原性遺伝子. 植物病害と遺伝子工学(大内成志, 豊田秀吉編), 朝日出版, 東京, pp. 124-134.

 

西村正暘, 柘植尚志, 田辺憲太郎, 中塚進一, 馮　柏年, 後藤俊夫 (1989). 宿主特異的毒素：植物病原糸状菌の病原性因子研究のモデル. 情報伝達物質による生物間化学交信, 新化学発展協会, つくば, pp. 1-12.

 

柘植尚志, 足立嘉彦, 田辺憲太郎 (1989). RFLP法－植物病原糸状菌の生態研究への応用－. 土壌伝染病談話会レポート 14: 18-25.

 

柘植尚志 (1987). Alternaria alternataの宿主特異的毒素と病原性に関する研究. 日植病報 53: 290.

 

柘植尚志, 小林裕和 (1987). 糸状菌の分子生物学－植物病原菌の宿主特異性を決定する遺伝情報の検索. 植物核酸タンパク質NEWS 38: 3-11.

 

柘植尚志, 小林裕和 (1987). 植物病原糸状菌における病原性に関与する遺伝子のクローニング. 植物感染生理談話会論文集（第24号）植物病理学分野における遺伝子操作(大内成志編), 日本植物病理学会, 東京, pp. 45-59.

 

柘植尚志, 西村正暘 (1986). Alternaria属菌の宿主特異的毒素－最近の研究動向－. 植物防疫 40: 395-402.

 

柘植尚志, 林　律器 (1984). 宿主特異的毒素依存Alternaria alternata病原菌群における病原性の制御. 植物感染生理談話会論文集（第21号）植物病原菌の病原性とその制御(獅山慈孝編), 日本植物病理学会, 東京, pp. 8-14.